Patient Autonomy and Incidental Findings in Clinical Genomics
نویسندگان
چکیده
منابع مشابه
Point-counterpoint. Patient autonomy and incidental findings in clinical genomics.
1049 POLICYFORUM E xome and whole-genome sequenc-ing are rapidly moving into clinical application to aid diagnosis and treatment. However, a startling statement by the American College of Medical Genetics and Genomics (ACMG) may prove to be a stumbling block (1). Rather than reconfi rming well-established principles of patient autonomy and informed consent that have long applied in medical gene...
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Ovarian incidentalomas are reported in 5-18% of asymptomatic females in cross sectional imaging. Even in oncologic patients the majority of these lesions will be benign, with hydrosalpinx and ovarian cysts as leading diagnoses. Special emphasis should be given to adnexal lesions in patients with history of primaries from the GI tract or breast cancer, both of which have a propensity to metastas...
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Recent advances in multidetector CT, magnetic resonance imaging, and ultrasound have led to the detection of incidental pancreatic and splenic lesions that in the past remained undiscovered. These incidentalomas are unexpected, asymptomatic abnormalities discovered serendipitously while searching for other pathology. These incidental lesions have created a management dilemma for both clinicians...
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AIMS Cardiac magnetic resonance (CMR) imaging benefits from a large field of view, but consequently captures incidental extra-cardiac findings (IEFs). There is a relative paucity of data for CMR in this regard. Our objectives were to assess the frequency and significance of IEFs reported from clinically indicated CMR scans, and additionally to ascertain if reporting rates differed between radio...
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ژورنال
عنوان ژورنال: Science
سال: 2013
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.1239119